|
|
Analysis of intracranial pressure
Procházka, Ondřej ; Kolářová, Jana (referee) ; Kozumplík, Jiří (advisor)
The aim of my bachelor’s work is the literature review about problematic of measurement and evaluation of intracranial pressure. I describe physical principle of intracranial pressure, anatomy of cerebral ventricle and different accesses and placement of measuring instruments in intracranial place. Moreover I describe evaluation of clinical data at standard way and explain analysis in frequency and time domain by program MATLAB. I make a script for analysis ICP data. It calculates main ICP, amplitude and latency of waves, RAP index and shows spectrum of amplitude.
|
|
|
Normal pressure hydrocephalus- Complex approach to diagnosis and treatment
Skalický, Petr ; Bradáč, Ondřej (advisor) ; Haninec, Pavel (referee) ; Keller, Jiří (referee)
Normal pressure hydrocephalus (NPH) is an important part of the differential dia- gnosis of the causes of cognitive deficit, gait disorder and incontinence in elderly patients. This is especially true for idiopathic normal pressure hydrocephalus (iNPH), to which this thesis is dominantly devoted. A number of factors contribute to the course of the disease, therefore a comprehensive approach evaluating multiple variables accompanying the disease, comorbid diseases or considered diseases in the differential diagnosis, as well as a comprehensive approach to therapy, which contains much more than just the im- plantation of a derivation system for the drainage of cerebrospinal fluid, can improve, not only, the quality of life of these patients. The mainstay of the dissertation thesis are two first-author articles. The first study deals with morphological parameters obtained during MRI examination and their ability to predict improvement in gait after shunt implantation in iNPH patients. We evaluated the predictive performance of score for evaulating disproportionately enlarged subarachnoid space hydrocephalus (DESH score), callosal angle and cingulate sulcus sign against the reference standard in the form of functional testing - lumbar infusion test (LIT) and external lumbar drainage (ELD). In the...
|
|
|
Deriving predictive pathophysiological markers from ICP analysis
Mládek, Arnošt ; Bradáč, Ondřej (advisor) ; Haninec, Pavel (referee) ; Mraček, Jan (referee)
Deriving predictive pathophysiological markers from ICP analysis RNDr. Arnošt Mládek, Ph.D. December 13, 2021 Abstract Intracranial pressure (ICP) is an irreplaceable neurointensive care parameter and is an area under intensive research. The great diagnostic importance of ICP is underlied by two factors: (1) the central nervous system (CNS) is placed in a rigid cranial vault and even small local expansive processes (e.g. tumors, abscesses, bleeding) may lead to intracranial hypertension; (2) a specific property of the CNS is a rather uniform response to various pathological events since many etiologically heterogeneous diffuse injuries of neural tissue lead to oedema elevating ICP. The complexity of ICP monitoring stems from the neurosurgical insertion of the pressure sensor into the intracranial space and the associated risks of bleeding, neuroinfection and brain tissue damage. Intracranial pressure is more than just a number on a bedside monitor, even though in clinical practice this simplification is rather common. Similarly to electrocardiogram (ECG) signals whose information content goes well beyond heart rate calculation, understanding of ICP dynamics can provide us with insight into the current clinical status as well as prediction of further evolution. The mainstay of the dissertation thesis are...
|
|
|
Analysis of intracranial pressure
Procházka, Ondřej ; Kolářová, Jana (referee) ; Kozumplík, Jiří (advisor)
The aim of my bachelor’s work is the literature review about problematic of measurement and evaluation of intracranial pressure. I describe physical principle of intracranial pressure, anatomy of cerebral ventricle and different accesses and placement of measuring instruments in intracranial place. Moreover I describe evaluation of clinical data at standard way and explain analysis in frequency and time domain by program MATLAB. I make a script for analysis ICP data. It calculates main ICP, amplitude and latency of waves, RAP index and shows spectrum of amplitude.
|
guest ::
